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Clinical Proteomics

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The entire approach how we diagnose and make treatment decisions is undergoing a paradigm shift in form of precision medicine, where targeted drugs are tailored for an individual patient based on extensive and informative biomarker data. Our mission is to advance precision medicine through state-of-the-art biological mass spectrometry (MS).

Clinical proteomics makes it possible to measure thousands of proteins, their variants, and post-translational modifications directly from clinical samples—going far beyond traditional single-marker assays. With the latest generation of mass spectrometers (Orbitrap Astral, ion mobility TOF) and automated, high-throughput workflows, our unit provides unique opportunities to:

  • Identify clinically relevant biomarkers
  • Stratify patients with greater precision
  • Support translational and clinical research with robust, reproducible data

The clinical proteomics activities within BioMS Sweden are distributed across Lund University, University of Gothenburg, and Karolinska Institutet, forming a coordinated national effort within the Swedish infrastructure for biological mass spectrometry.
All three sites actively participate in Proteome Medicine Sweden (ProMS), contributing complementary expertise and capabilities to advance clinical proteomics and precision medicine.

The Clinical Proteomics Lund unit is hosted at Lund University and operates as part of the SciLifeLab Proteomics platform, contributing specialized expertise and services to both BioMS Sweden and the national ProMS initiative.

The unit builds on strong local collaborations with healthcare and the university hospital regions, as well as extensive expertise in biomarker development, and translational clinical studies. From our base in Lund, and with mirrored instrumentation also established at GU and KI, we enable synchronized, large-scale, and prospective analyses across Sweden—supporting national clinical trials and biobank studies.

Interested?

We encourage researchers from academia, healthcare, and industry to contact us early in the project planning phase. Our team can advise on study design, sample handling, and method selection to ensure high-quality and clinically relevant results.

For further information, please contact us below:

biomslund@epic.lu.se (Clinical Proteomics Lund, Lund University)
pcf@gu.se (BioMS Node, University of Gothenburg)
proteomicscore@scilifelab.se (BioMS Node, Karolinska Institutet)